CosMx™ Human Immuno-Oncology Panel
みなさまの研究の一助に
ヒトシングルセル空間RNA解析
CosMx Human Immuno-Oncology Panel は、主要な免疫細胞および間質細胞の細胞タイピング、ならびに免疫浸潤および腫瘍微小環境の評価のために最適化されています。 免疫細胞とそれらの活動、およびIO療法に関連する腫瘍生物学の側面をカバーする100の転写産物の発現をプロファイリングし、最大10個の独自のターゲットでのカスタマイズも可能です。
論文&ポスター
Characterizing Late-Onset AD Models Using Spatial Whole Transcriptome Analysis – AGBT 2021
Smarca4-deficient lung cancers display a metastatic-like cell state and a distinct cell-of-origin – AGBT 2021
Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
Synovial sarcoma (SyS) is an aggressive neoplasm driven by the SS18-SSX fusion, and is characterized by low T cell infiltration. Here, we studied the cancer-immune interplay in SyS using an integrative approach that combines single-cell RNA sequencing (scRNA-seq), spatial profiling and genetic and pharmacological perturbations.
The spatial landscape of lung pathology during COVID-19 progression
Recent studies have provided insights into the pathology and immune response to coronavirus disease 2019 (COVID-19)1–8. However, thorough interrogation of the interplay between infected cells and the immune system at sites of infection is lacking.
Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection
The relationship of SARS-CoV-2 pulmonary infection and severity of disease is not fully understood. Here we show analysis of autopsy specimens from 24 patients who succumbed to SARS-CoV-2 infection using a combination of different RNA and protein analytical platforms to characterize inter-patient and intra-patient heterogeneity of pulmonary virus infection.
