Pharma & CRO Spatial Summit: バイオマーカー探索の次の時代を強化-日本版
海外の製薬企業やCROが「GeoMx®デジタル空間プロファイラー(DSP)とCosMx™空間分子イメージャー(SMI)を、がんおよび治療反応の次世代バイオマーカーの発見に利用しています。製薬での空間解析の利用について、ナノストリングとイルミナが共催した海外版ウェビナーを、英語字幕を入れて日本版として放送いたします。
Janssen社のJoshua Rusbuldtは、GeoMxを薬物探索のための空間生物学プラットフォームとして非常に利用していただいています。Presage Biosciences社CEOのRich Klinghoffer博士は、GeoMx DSPとCosMx SMIを使用して、第0相臨床試験における治験薬の腫瘍微環境への影響を特徴づけた方法についてご説明されます。 ナノストリングの計算生物学部門のAssociate DirectorのJason Reevesより、空間的に解像された遺伝子およびタンパク質発現データの解析について考察いたします。またイルミナ社より、GeoMxのリードアウトに必要なNextSeq™ 2000システムのシーケンス能力の概要についてご説明いただきます。
共催企業:イルミナ株式会社
Time | Theme | Title | Speaker |
20min | nPowering the next Era of Biomarker Discovery with GeoMx® DSP and CosMx™ SMI | 谷家 貴之 PhD, ナノストリング・テクノロジーズ | |
25min | Integration of Spatial Biology Platforms with Drug Discovery | Spatial ‘omics platforms, led by the technologies developed by NanoString, offer high plex and high resolution profiling of precious specimens. | Joshua J. Rusbuldt, MASenior Scientist, Immunology Translational Sciences – Gastroenterology, Janssen Pharmaceuticals |
14min | Key Considerations for Successful Spatial Biology Studies | Spatial biology approaches can reveal novel insights to empower drug discovery and development programs however ensuring successful study outcomes is by no means trivial. Sirona Dx has pioneered spatial biology services to biopharma since 2018 and in this short presentation we will introduce our leading edge capabilities and highlight elements of study design that are critical to success. | Andrew Brown, PhDChief Commercial Officer, Sirona Dx |
24min | Revolutionizing translational oncology: Detailed understanding of drug effects in patient tumors through “functional spatial profiling | Tumor response to drug exposure is highly influenced by the composition and activity state of the tumor microenvironment (TME). To bridge the gap between the evaluation of new investigational agents in laboratory models and clinical studies. | Rich Klinghoffer, PhD CEO Presage Biosciences |
25min | Strategies for Success: Harnessing GeoMx and CosMx Data for Pharma and CRO Applications | Join us as we explore the power of GeoMx DSP and CosMx SMI data analysis for biomarker discovery and drug development pipelines. This talk equips you with practical strategies to maximize the utility of GeoMx DSP and CosMx SMI data, enhancing decision-making, and accelerating breakthroughs in the dynamic field of biopharma and biomedical research. | Jason Reeves, PhDAssociate Director, Bioinformatics, NanoString |
15min | Streamline spatial sequencing with NextSeqTM 1000/2000 and GeoMx | 山重りえ, イルミナ株式会社セグメントマーケティング部 |
The CosMx™ SMI and decoder probes are not offered and/or delivered to the Federal Republic of Germany for use in the Federal Republic of Germany for the detection of cellular RNA, messenger RNA, microRNA, ribosomal RNA and any combinations thereof in a method used in fluorescence in situ hybridization for detecting a plurality of analytes in a sample without the consent of the President and Fellows of Harvard College (Harvard Corporation) as owner of the German part of EP 2 794 928 B1. The use for the detection of cellular RNA, messenger RNA, microRNA, ribosomal RNA and any combinations thereof is prohibited without the consent of the President and Fellows of Harvard College (Harvard Corporation).